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Studies & Scientific References

All recommendations in our Wiki articles are based on current scientific evidence. Here you will find the most important studies and references on which our medical statements are based — verifiable, with DOI and PubMed link.

Why citations are important

Marketing promises are one thing. Clinical evidence is another. We want you to be able to verify our claims — and see that they are based on internationally recognized research.

The following list is not exhaustive — it presents the key studies on which our recommendations for methods, active ingredients, and treatment procedures are based.

The list is continuously updated as new relevant studies are published.

Transplantation Methods

FUE Method — Fundamentals

Rassman WR et al. Follicular Unit Extraction: Minimally invasive surgery for hair transplantation. Dermatol Surg. 2002;28(8):720-728.
PubMed: 12174065

Harris JA. The SAFE System: New instrumentation and methodology to improve follicular unit extraction (FUE). Hair Transplant Forum International. 2004;14(5):157-163.

Sapphire FUE vs. Steel Blade

Garg AK, Garg S. Sapphire blade in hair transplantation: A review. Indian Dermatology Online Journal. 2018;9(2):91-97.
doi: 10.4103/idoj.IDOJ_232_17

Growth Rates — Standards

Beehner M. A comparison of hair growth between follicular-unit grafts trimmed „skinny“ vs. „chubby“. Dermatologic Surgery. 1999;25(4):339-340.

Avram MR et al. Hair transplantation outcomes: A comprehensive review. Plast Reconstr Surg. 2014;134(4):595-607.
doi: 10.1097/PRS.0000000000000565

Conservative Treatment Options

The scientific evidence for various conservative treatment approaches is extensive. For legal reasons, we refrain from providing a detailed list of prescription drug studies on a publicly accessible website.

During a personal consultation, we will transparently and comprehensively discuss the individually relevant treatment options for you and the underlying studies.

PRP & Regenerative Procedures

PRP for Hair Loss — Meta-analyses

Gupta AK et al. A systematic review of platelet-rich plasma in the treatment of androgenetic alopecia. Dermatologic Surgery. 2019;45(7):1019-1029.

Giordano S et al. Platelet-rich plasma for androgenetic alopecia: A systematic review and meta-analysis. J Cosmet Dermatol. 2017;16(3):374-381.

Alves R, Grimalt R. Randomized placebo-controlled, double-blind, half-head study to assess the efficacy of platelet-rich plasma on the treatment of androgenetic alopecia. Dermatologic Surgery. 2016;42(4):491-497.

PRP in Women

Bruce AJ et al. A randomized, controlled pilot trial of platelet-rich plasma for androgenic alopecia in women. Dermatologic Surgery. 2020;46(6):826-832.

Microneedling Combination

Dhurat R et al. A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichology. 2013;5(1):6-11.

Exosomes (current research status)

Kuka G et al. Use of exosomes from human placenta in androgenetic alopecia treatment. Aesthetic Plast Surg. 2023;47(2):793-801.

Anatomy & Biology

Hair Growth Cycle

Stenn KS, Paus R. Controls of hair follicle cycling. Physiological Reviews. 2001;81(1):449-494.
doi: 10.1152/physrev.2001.81.1.449

DHT Mechanism in Androgenetic Alopecia

Kaufman KD. Androgens and alopecia. Mol Cell Endocrinol. 2002;198(1-2):89-95.

Hibberts NA et al. Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp. J Endocrinol. 1998;156(1):59-65.

Donor Dominance

Orentreich N. Autografts in alopecias and other selected dermatological conditions. Ann N Y Acad Sci. 1959;83:463-479.

Classification Scales

Hamilton JB. Patterned loss of hair in man: types and incidence. Ann N Y Acad Sci. 1951;53(3):708-728.

Norwood OT. Male pattern baldness: classification and incidence. South Med J. 1975;68(11):1359-1365.

Ludwig E. Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex. Br J Dermatol. 1977;97(3):247-254.

Sinclair R. Male pattern androgenetic alopecia. BMJ. 1998;317(7162):865-869.

Savin RC. A method for visually describing the stages of male pattern baldness. Hair Transplant Forum International. 1994;4(7):4-5.

Note on Timeliness

This list of studies includes key references — both historical foundational publications and current meta-analyses. The list is continuously reviewed and updated.

We follow the recommendations of the following medical professional societies:

  • VDHC — Association of German Hair Surgeons
  • EHRS — European Hair Research Society
  • ISHRS — International Society of Hair Restoration Surgery
  • DDG — German Dermatological Society

Our practice is a member of the VDHC and EHRS and regularly participates in international congresses and live surgery sessions.

If you have any questions about specific studies or further literature, please feel free to ask us during your initial consultation.

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